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In page Oxycodone:
"Oxycodone has a volume of distribution of 2.6L/kg,[1] in the blood it is distributed to skeletal muscle, liver, intestinal tract, lungs, spleen, and brain.[2] Conventional oral preparations start to reduce pain within 10 to 15 minutes on an empty stomach; in contrast, OxyContin starts to reduce pain within one hour.[3]
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