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In page Equine lymphangitis:

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The initial pain and lameness usually respond rapidly to treatment, but the swelling may persist for many weeks. In addition, once a horse has had an episode, it appears to be predisposed to recurrence, and may suffer from "filled legs" permanently – i.e. if left in a stable and relatively immobile, poor lymphatic circulation results in a passive oedema of the previously affected limb, that dissipates on exercise. In more severe cases, the limb may never return to normal size. In these cases, permanent scarring of the lymphatics and other tissues is likely. Treatment in these cases is unrewarding, and euthanasia may be indicated if the condition causes unmanageable lameness.