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In page Sherman paradox:
"Fragile X syndrome is so named because of the appearance of the X chromosome in individuals with fragile X. Under an electron microscope, a region on the long arm of the chromosome resembles a thin string. Investigation showed that this region consists of a CGG repeat triplet in both normal and diseased individuals.[2] The difference between normal and diseased is the length of the repeat; the repeat is longer where fragile X syndrome is present. When the length of the repeat surpasses a critical threshold, symptoms of the disorder appear and they increase in likelihood and severity with further length. Even below this threshold there is a range where the repeat becomes unstable during meiosis.
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