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In page Multiple subpial transection:
"At some epilepsy centers, patients are offered additional conventional or experimental medications before surgery is considered. However, research suggests that each time a trial of medication fails to control a person's seizures, it becomes less likely that a different medicine or combination will be successful. Since uncontrolled seizures present serious physical risks and social and psychological consequences, the trend these days is to proceed with surgery much sooner than in the past if it seems appropriate for that person.
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