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In page Hypericum calycinum:
"Recent research on mice has shown that the alcoholic extracts from Hypericum calycinum have antidepressant effects and are comparably as effective as antidepressant drugs, such as desipramine and trimipramine. Unlike the rest of the genus, H. calycinum does not have hypericin, which causes photosensitization, which causes the side effects of flush, fatigue, and pruritis when used in drugs. These extracts have the potential to be a remedy for depression without these side effects common in current antidepressants. However, more research is required.[3]
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