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In page Lactobacillus plantarum:

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As a result of initial HIV infection, the gut has been found to be a prime center of immune activity.[15] The immune systems' Paneth cells of the gut attack HIV by producing Interleukin 1 beta (IL-1β), which results in extensive collateral damage — sloughing of tight intestinal lining, witnessed as severe diarrhea. This destruction of the gut lining allows other pathogens to invade, e.g., Cryptococcus species, resulting in an AIDS-defining illness such as cryptococcosis, representing 60% to 70% of all AIDS-defining cases,[16] but not necessarily only the gut. L. plantarum is able to reduce (destroy) IL-1β, resolving inflammation, and accelerating gut repair within hours.[15]