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In page Leslie Orgel:
"For nucleoside (nucleobase + ribose sugar) synthesis, Orgel suggested an almost opposite approach, heating a mixture of ribose and the purine nucleobases hypoxanthine, adenine, and guanine to dryness in the presence of magnesium ions.[1] This reaction puts the glycosidic bond in the correct position in two ways: the nucleobase attaches to the correct carbon on ribose, and in the correct orientation (the beta anomer).
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